When the insomnia that we are just not doing, just to quickly go to the "kingdom of Morpheus". And elephants believe, and sheep - and in the end still almost until morning to turn. That would be a universal cure for insomnia. But, unfortunately, it has not come up (if not take pills). But you can make yourself sleep through other effective methods of insomnia.

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MedWorm Query: sleep

Sleeplessness linked to paranoia

Lack of sleep really can affect a person's sanity, with new research showing a clear link between insomnia and paranoid delusions (Source: Nursing in Practice)

Self-monitored sleep duration may allow bipolar mood change prediction

Bipolar disorder patients should self-monitor their sleep duration in order to predict mood change, recommend scientists who call for a greater understanding of the long sleep duration of euthymic patients. (Source: MedWire News - Psychiatry)

Excessive daytime sleepiness more common in obese children with habitual snoring

A study shows that the likelihood of excessive daytime sleepiness in obese children is greater vs nonobese children at any given level of severity of obstructive sleep apnea. Medscape Medical News (Source: Medscape Medical News Headlines)

Excessive daytime sleepiness more common in obese children with habitual snoring

A study shows that the likelihood of excessive daytime sleepiness in obese children is greater vs nonobese children at any given level of severity of obstructive sleep apnea. Medscape Medical News (Source: Medscape Medical News Headlines)

Sleep apnea as a cause of gout flares

A reader explains the need to examine the sleep patterns of patients being treated for gout. The Medscape Journal of Medicine (Source: Medscape Cardiology Headlines)

Arousals from sleep possible cause of apnea in some patients

TORONTO (MedPage Today) -- In patients with heart failure and central sleep apnea, arousals may cause the sleep disorder rather than defending against it, researchers here said. (Source: MedPage Today Geriatrics)

The high societal, economic burden of insomnia shown by study

A study in the Jan. 1 issue of the journal Sleep indicates that the indirect costs of untreated insomnia are significantly greater than the direct costs associated with its treatment. The study estimates that the total annual cost of insomnia in the province of Quebec is 6.5 billion Canadian dollars, representing about one percent of the province's $228. (Source: Health News from Medical News Today)

Factors other than central sleep apnea may contribute to poor sleep quality in heart-failure patients

A study in the Jan. 1 issue of the journal Sleep demonstrates that the frequent arousals from sleep that occur in heart failure patients with central sleep apnea (CSA) may reflect the presence of another underlying arousal disorder rather than being a defensive mechanism to terminate apneas. (Source: Health News from Medical News Today)

Inflammatory cardiovascular risk markers in obstructive sleep apnoea syndrome

(Source: Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Cardiovascular & Hematological Agents))

Is a purpose of rem sleep atonia to help regenerate intervertebral disc volumetric loss?

This article discusses a new hypothesis for complete core muscle relaxation in REM sleep, suggesting a bottom-up recuperative perspective. That is, does the atonia in REM sleep provide a utility to help restore the mechanobiology and respective diurnal intervertebral disc hydraulic loss? By combining the effects of gravity with current compressive concepts in spinal stability, this article looks at vertebral approximation as a deleterious experience with an intrinsic biological need to keep vertebrae separated. Methods using polysomnography and recumbent MRI are discussed. (Source: BioMed Central)

Strange sleep disorders: sexsomnia to sudden death

From sexual sleepwalking to dying of nightmares, science struggles with these sleeping riddles. (Source: CTV Health)

Can a sleep disorder predict parkinson's?

Scientists say a rare sleep disorder may be a precursor to the eventual onset of severe symptoms of the disease (Source: TIME: Top Science and Health Stories)

Lack of sleep linked to heart problems

A new study indicates that coronary calcium, the kind that may cause heart attacks and strokes, increases the fewer hours you sleep (Source: TIME: Top Science and Health Stories)

Disorders of arousal from sleep and violent behavior: the role of physical contact and proximity. - pressman mr.

STUDY OBJECTIVES: To review medical and legal case reports to determine how many appear to support the belief that violence against other individuals that occurs during Disorders of Arousal - sleepwalking, confusional arousal, and sleep terrors - is trigge... (Source: SafetyLit: All (Unduplicated))

Effects of context on sleepiness self-ratings during repeated partial sleep deprivation. - akerstedt t, kecklund g, axelsson j.

Ratings of subjective sleepiness are often used in laboratory and field studies of sleep loss and shifted sleep hours. Some studies suggest that such ratings might fail to reflect sleepiness as shown in physiology or performance. One reason for this may be... (Source: SafetyLit: All (Unduplicated))

Effects of modafinil and sleep loss on physiological parameters. - cuddy js, reinert ar, hansen kc, ruby bc.

OBJECTIVE: The purpose of this study was to determine the effects of modafinil administration on physical performance, thermoregulation, and total energy expenditure (TEE) during continued wakefulness in Air Force operators. METHODS: Participants (N = 12) ... (Source: SafetyLit: All (Unduplicated))

Exploring the effects of lifestyle, sleep factors and driving behaviors on sleep-related road risk: a study of greek drivers. - papadakaki m, kontogiannis t, tzamalouka g, darviri c, chliaoutakis j.

PURPOSE: The present study explored the effect of various lifestyle patterns and sleep-related factors on the sleep-related road risk. Sleep-related factors included daytime sleepiness, drowsy driving and quality/quantify of sleep. METHODS: A sample of 136... (Source: SafetyLit: All (Unduplicated))

Medico-legal implications of sleep apnoea syndrome: driving license regulations in europe. - alonderis a, barbé f, bonsignore m, calverley p, de backer w, diefenbach k, donic v, fanfulla f, fietze i, franklin k, grote l, hedner j, jennum p, krieger j, levy p, mcnicholas w, montserrat j, parati g, pascu m, penzel t, riha r, rodenstein d, sanna a, schulz r, sforza e, sliwinski p, tomori z, tonnesen p, varoneckas g, zielinski j, kostelidou k.

[ePub (volume, issue, and page range not yet available)] BACKGROUND: Sleep apnoea syndrome (SAS), one of the main medical causes of excessive daytime sleepiness, has been shown to be a risk factor for traffic accidents. Treating SAS results in a no... (Source: SafetyLit: All (Unduplicated))

Effects of moderate sleep deprivation and low-dose alcohol on driving simulator performance and perception in young men. - vakulin a, baulk sd, catcheside pg, anderson r, van den heuvel cj, banks s, mcevoy rd.

STUDY OBJECTIVE: To determine the combined effects of sleep restriction and low-dose alcohol on driving simulator performance, EEG, and subjective levels of sleepiness and performance in the mid-afternoon. DESIGN: Repeated measures with 4 experimental cond... (Source: SafetyLit: All (Unduplicated))

Alzheimer's society comment on research suggesting that sleep disorder may be an early sign of dementia or parkinson's disease

People who act out their dreams through kicking and crying out in their sleep may go on to develop dementia or Parkinson's disease, according to a study published in the online issue of Neurology. In the research 93 people with REM sleep behaviour disorder who had no signs of a neurodegenerative disease were followed for an average of five years. (Source: Health News from Medical News Today)

Undiagnosed sleep problems may lead to long-term health issues

Sixteen percent of Georgia’s residents experience persistent problems staying awake during the day, according to a study by the Centers for Disease Control and Prevention (CDC) and published online in the American Journal of Epidemiology. This research points to the importance of diagnosing and treating sleep problems before they could potentially develop into long term health issues. (Source: NurseZone.com Nursing News)

Sensory hypersensitivity as a contributing factor in the relation between sleep and behavioral disorders in normal schoolchildren.

Authors: Shochat T, Tzischinsky O, Engel-Yeger B Despite growing interest in the relationship between sleep disturbances and behavioral disorders-specifically, symptoms of attention deficit/hyperactivity disorder (ADHD) in children-the underlying structure of this relationship is poorly understood. The aim of the study was to explore the contribution of sensory hypersensitivity to this relationship. Parents of 56 schoolchildren completed questionnaires reporting sleep habits, behavior, and sensory processing. Significant correlations were found between global scores of all 3 constructs; however, the relationship between sleep and behavior decreased when controlling for sensory processing. Among different sensory modalities, tactile sensitivity was a significant predictor for sleep, acc...

Characteristics of individuals with insomnia who seek treatment in a clinical setting versus those who volunteer for a randomized controlled trial.

This study compared sociodemographic, sleep, psychological, and medical characteristics of individuals who volunteered for an insomnia treatment study (n = 120) to patients who sought treatment in a clinical setting (n = 106). The samples did not differ on most sleep and medical variables, but clinical patients had a higher prevalence of mood disorders, greater anxiety and depression symptoms, and higher perceived insomnia severity. Differences on psychological variables were accentuated by the research selection process. It is suggested to minimize exclusion based on psychological comorbidity in order to enhance ecological validity of randomized controlled trials of insomnia treatments. PMID: 19116800 [PubMed - in process] (Source: Behavioral Sleep Medicine)

Relationship quality and cpap adherence in patients with obstructive sleep apnea.

Relationship quality and CPAP adherence in patients with obstructive sleep apnea. Behav Sleep Med. 2009;7(1):22-36 Authors: Baron KG, Smith TW, Czajkowski LA, Gunn HE, Jones CR The prospective influence of relationship support and conflict on adherence to continuous positive airway pressure (CPAP) was examined over the first 3 months of CPAP treatment in 42 married, male patients with obstructive sleep apnea (OSA). CPAP adherence reports were available for 23 patients. Patient ratings of marital conflict predicted average nightly adherence (beta = -0.357, p < .05), but ratings of marital support did not predict adherence. Three-month follow-up ratings of marital support and conflict, subjective sleepiness, depression, and functional impairment were available for 16 patients ...

Commentary on "marital happiness and sleep disturbances in a multi-ethnic sample of middle-aged women".

Authors: Cartwright R PMID: 19116798 [PubMed - in process] (Source: Behavioral Sleep Medicine)

Marital happiness and sleep disturbances in a multi-ethnic sample of middle-aged women.

Authors: Troxel WM, Buysse DJ, Hall M, Matthews KA Previous research suggests that divorced individuals, particularly women, have higher rates of sleep disturbances as compared to married individuals. Among the married, however, little is known about the association between relationship quality and sleep. The present study examined the association between marital happiness and self-reported sleep disturbances in a sample of midlife women drawn from the Study of Women's Health Across the Nation (SWAN), a multi-site, multi-ethnic, community-based study (N = 2,148). Marital happiness was measured using a single item from the Dyadic Adjustment Scale, and sleep disturbance was assessed using 4 items from the Women's Health Initiative Insomnia Rating Scale (WHIIRS). After controlling for rel...

Early career distinguished research award.

Authors: PMID: 19116796 [PubMed - in process] (Source: Behavioral Sleep Medicine)

Sleep promotes generalization of extinction of conditioned fear

Conclusions: After sleep, extinction memory generalized from an extinguished conditioned stimulus to a similarly conditioned but unextinguished stimulus. Clinically, adequate sleep may promote generalization of extinction memory from specific stimuli treated during exposure therapy to similar stimuli later encountered in vivo. Keywords: Fear conditioning, extinction, generalization, human, emotional memory (Source: Sleep)

The economic burden of insomnia: direct and indirect costs for individuals with insomnia syndrome, insomnia symptoms, and good sleepers

Conclusions: This study suggests that the economic burden of insomnia is very high, with the largest proportion of all expenses (76%) attributable to insomnia-related work absences and reduced productivity. As the economic burden of untreated insomnia is much higher than that of treating insomnia, future clinical trials should evaluate the cost-benefits, cost-utility, and cost-effectiveness of insomnia therapies. Keywords: Insomnia, epidemiology, health economics (Source: Sleep)

Race and financial strain are independent correlates of sleep in midlife women: the swan sleep study

Conclusions: Independent relationships between race and financial strain with sleep were observed despite statistical adjustment for other factors that might account for these relationships. Results do not suggest that assessed indices of SES moderate the race-sleep relationship, perhaps due to too few women of low SES in the study. Keywords: sleep; power spectral analysis; PSQI; midlife women; menopause; race; SES (Source: Sleep)

Effect of continuous positive airway pressure on sleep structure in heart failure patients with central sleep apnea

Conclusion: These data suggest that attenuation of CSA by CPAP does not reduce arousal frequency in HF patients. We conclude that arousals were not mainly a consequence of CSA, and may not have been acting as a defense mechanism to terminate apneas in the same way they do in OSA. Keywords:Arousal, sleep structure, central sleep apnea, sleep physiology (Source: Sleep)

A human model that suggests a role for sleep in the cognitive neuropsychology of ptsd and recovery

(Source: Sleep)

Craniofacial profile assessment in patients with obstructive sleep apnea

A commentary on Lee et al. Craniofacial Phenotyping in Obstructive Sleep Apnea – A Novel Quantitative Photographic Approach. SLEEP 2008;32:37-45. and Lee et al. Prediction of Obstructive Sleep Apnea with Craniofacial Photographic Analysis. Sleep 2009;32:46-52. (Source: Sleep)

Heart failure, central sleep apnea, cpap, and arousals: another piece of the puzzle

A commentary on Ruttanaumpawan et al. Effect of Continuous Positive Airway Pressure on Sleep Structure in Heart Failure Patients with Central Sleep Apnea. Sleep 2009;32:91-98. (Source: Sleep)

Discovery of the dreaming sleep stage: a recollection

(Source: Sleep)

Re-redefining success in airway surgery for obstructive sleep apnea

(Source: Sleep)

Effects and side-effects of surgery for snoring and obstructive sleep apnea – a systematic review

Conclusions: Only a small number of randomized controlled trials with a limited number of patients assessing some surgical modalities for snoring or sleep apnea are available. These studies do not provide any evidence of effect from laser-assisted uvulopalatoplasty or radiofrequency ablation on daytime sleepiness, apnea reduction, quality of life or snoring. We call for research of randomized, controlled trials of surgery other than uvulopalatopharyngoplasty and uvulopalatoplasty, as they are related to a high risk of long-term side-effects, especially difficulty swallowing. Keywords: Sleep apnea syndromes, snoring, surgery, adverse effects, meta-analysis (Source: Sleep)

Craniofacial phenotyping in obstructive sleep apnea – a novel quantitative photographic approach

Conclusions: Craniofacial phenotypic differences in OSA in Caucasian subjects can be demonstrated using a photographic analysis technique. Keywords: obstructive sleep apnea; craniofacial abnormalities; photogrammetry; phenotype (Source: Sleep)

Prediction of obstructive sleep apnea with craniofacial photographic analysis

(Source: Sleep)

Insomnia did not predict incident hypertension in older adults in the cardiovascular health study

Conclusions:Insomnia did not predict hypertension in this older cohort which was free of hypertension at baseline. Difficulty falling asleep was associated with reduced risk of hypertension in non-African American men. Keywords: Aging, sleep complaints, cardiovascular disease, epidemiology, African American (Source: Sleep)

Development of nrem sleep instability-continuity (cyclic alternating pattern) in healthy term infants aged 1 to 4 months

Conclusions: With this study, we provide the first data on CAP analysis in infants from 1 to 4 months of life, and we found that there is a transitory period when tracè alternant disappears and CAP events begin to occur. Furthermore, we suggest that the more appropriate time of life when CAP analysis can be first performed is related to the appearance of mature stage 2 NREM with spindles and slow delta waves mixed with theta waves, at approximately 3 months of life. Keywords: Infant, cyclic alternating pattern, arousal, tracè alternant (Source: Sleep)

Irregular respiration as a marker of wakefulness during titration of cpap

Conclusions: Despite not detecting all wakefulness, the high positive predictive value suggests that analysis of the respiration signal alone may be a useful indicator of CNS state with potential utility in the control of CPAP in OSAHS. The present study demonstrates the feasibility of automating the detection of IrREG. Keywords: Sleep disordered breathing, artificial neural network, autotitration, arousal and wakefulness, obstructive sleep apnea (Source: Sleep)

Prevalence and correlates of insomnia and its impact on quality of life in chinese schizophrenia patients

Conclusion: Insomnia is independently associated with poor QOL. More attention should be paid in clinical practice to the high rate of insomnia in Chinese schizophrenia patients. Keywords: Schizophrenia, insomnia, quality of life, China, Hong Kong (Source: Sleep)

A consensus definition of cataplexy in mouse models of narcolepsy

People with narcolepsy often have episodes of cataplexy, brief periods of muscle weakness triggered by strong emotions. Many researchers are now studying mouse models of narcolepsy, but definitions of cataplexy-like behavior in mice differ across labs. To establish a common language, the International Working Group on Rodent Models of Narcolepsy reviewed the literature on cataplexy in people with narcolepsy and in dog and mouse models of narcolepsy and then developed a consensus definition of murine cataplexy. The group concluded that murine cataplexy is an abrupt episode of nuchal atonia lasting at least 10 seconds. In addition, theta activity dominates the EEG during the episode, and video recordings document immobility. To distinguish a cataplexy episode from REM sleep after a brief awa...

Obstructive apneas induce early release of mesenchymal stem cells into circulating blood

Conclusions: Application of a pattern of airway obstructions similar to those experienced by patients with sleep apnea induced an early mobilization of mesenchymal stem cells into circulating blood. Keywords: Obstructive sleep apnea, animal model, airway obstruction, circulating stem cells, bone marrow cells, mesenchymal stem cells (Source: Sleep)

[horizontal ellipsis]about sleep.

About sleepPage: 63DOI: 10.1097/01.NURSE.0000343463.63321.ce (Source: Nursing)

Testing for a primary sleep disorder

Dr. W. Vaughn McCall answers a question about testing for a primary sleep disorder in a 30-year-old woman with insomnia and depression. Medscape Neurology & Neurosurgery (Source: Medscape FamilyMedicine Headlines)

Richard dawkins: blurring the human/animal boundary

In a late response to Edge.org's annual New Year challenge to the world's leading thinkers, Prof Richard Dawkins has submitted his entry. Edge.org asked scientists, philosophers, artists and journalists "What will change everything?"Dawkins – author of The Selfish Gene and The God Delusion – muses on the effect of breaking down the barrier between humans and animals, perhaps by the creation of a chimera in a lab or a "successful hybridisation between a human and a chimpanzee". Here's what he had to say.Breaking the species barrierOur ethics and our politics assume, largely without question or serious discussion, that the division between human and 'animal' is absolute. 'Pro-life', to take just one example, is a potent political badge, associated with a gamut of ethical issues such as o...

How much is cost to be sleepless?

Westchester, Ill. A study in the Jan. 1 issue of the journal Sleep indicates that the indirect costs of untreated insomnia are significantly greater than the direct costs linked to its therapy. The study estimates that the total annual cost of insomnia in the province of Quebec is 6.5 billion Canadian dollars, representing about one percent of the province's $228.5 billion in gross domestic product for 2002........ (Source: Medicineworld.org: New Article Alert)

Hypertrophic obstructive cardiomyopathy and sleep-disordered breathing: an under-recognized and unfavorable association

Could obstructive sleep apnea be the reason cardiomyopathy symptoms remain for some patients, despite medical therapy? Nature Clinical Practice Cardiovascular Medicine (Source: Medscape Cardiology Headlines)

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