When the insomnia that we are just not doing, just to quickly go to the "kingdom of Morpheus". And elephants believe, and sheep - and in the end still almost until morning to turn. That would be a universal cure for insomnia. But, unfortunately, it has not come up (if not take pills). But you can make yourself sleep through other effective methods of insomnia.

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MedWorm: Sleep Medicine

Early career distinguished research award.

Authors: PMID: 19116796 [PubMed - in process] (Source: Behavioral Sleep Medicine)

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Marital happiness and sleep disturbances in a multi-ethnic sample of middle-aged women.

Authors: Troxel WM, Buysse DJ, Hall M, Matthews KA Previous research suggests that divorced individuals, particularly women, have higher rates of sleep disturbances as compared to married individuals. Among the married, however, little is known about the association between relationship quality and sleep. The present study examined the association between marital happiness and self-reported sleep disturbances in a sample of midlife women drawn from the Study of Women's Health Across the Nation (SWAN), a multi-site, multi-ethnic, community-based study (N = 2,148). Marital happiness was measured using a single item from the Dyadic Adjustment Scale, and sleep disturbance was assessed using 4 items from the Women's Health Initiative Insomnia Rating Scale (WHIIRS). After controlling for rel...

Commentary on "marital happiness and sleep disturbances in a multi-ethnic sample of middle-aged women".

Authors: Cartwright R PMID: 19116798 [PubMed - in process] (Source: Behavioral Sleep Medicine)

Relationship quality and cpap adherence in patients with obstructive sleep apnea.

Relationship quality and CPAP adherence in patients with obstructive sleep apnea. Behav Sleep Med. 2009;7(1):22-36 Authors: Baron KG, Smith TW, Czajkowski LA, Gunn HE, Jones CR The prospective influence of relationship support and conflict on adherence to continuous positive airway pressure (CPAP) was examined over the first 3 months of CPAP treatment in 42 married, male patients with obstructive sleep apnea (OSA). CPAP adherence reports were available for 23 patients. Patient ratings of marital conflict predicted average nightly adherence (beta = -0.357, p < .05), but ratings of marital support did not predict adherence. Three-month follow-up ratings of marital support and conflict, subjective sleepiness, depression, and functional impairment were available for 16 patients ...

Characteristics of individuals with insomnia who seek treatment in a clinical setting versus those who volunteer for a randomized controlled trial.

This study compared sociodemographic, sleep, psychological, and medical characteristics of individuals who volunteered for an insomnia treatment study (n = 120) to patients who sought treatment in a clinical setting (n = 106). The samples did not differ on most sleep and medical variables, but clinical patients had a higher prevalence of mood disorders, greater anxiety and depression symptoms, and higher perceived insomnia severity. Differences on psychological variables were accentuated by the research selection process. It is suggested to minimize exclusion based on psychological comorbidity in order to enhance ecological validity of randomized controlled trials of insomnia treatments. PMID: 19116800 [PubMed - in process] (Source: Behavioral Sleep Medicine)

Sensory hypersensitivity as a contributing factor in the relation between sleep and behavioral disorders in normal schoolchildren.

Authors: Shochat T, Tzischinsky O, Engel-Yeger B Despite growing interest in the relationship between sleep disturbances and behavioral disorders-specifically, symptoms of attention deficit/hyperactivity disorder (ADHD) in children-the underlying structure of this relationship is poorly understood. The aim of the study was to explore the contribution of sensory hypersensitivity to this relationship. Parents of 56 schoolchildren completed questionnaires reporting sleep habits, behavior, and sensory processing. Significant correlations were found between global scores of all 3 constructs; however, the relationship between sleep and behavior decreased when controlling for sensory processing. Among different sensory modalities, tactile sensitivity was a significant predictor for sleep, acc...

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Obstructive apneas induce early release of mesenchymal stem cells into circulating blood

Conclusions: Application of a pattern of airway obstructions similar to those experienced by patients with sleep apnea induced an early mobilization of mesenchymal stem cells into circulating blood. Keywords: Obstructive sleep apnea, animal model, airway obstruction, circulating stem cells, bone marrow cells, mesenchymal stem cells (Source: Sleep)

A consensus definition of cataplexy in mouse models of narcolepsy

People with narcolepsy often have episodes of cataplexy, brief periods of muscle weakness triggered by strong emotions. Many researchers are now studying mouse models of narcolepsy, but definitions of cataplexy-like behavior in mice differ across labs. To establish a common language, the International Working Group on Rodent Models of Narcolepsy reviewed the literature on cataplexy in people with narcolepsy and in dog and mouse models of narcolepsy and then developed a consensus definition of murine cataplexy. The group concluded that murine cataplexy is an abrupt episode of nuchal atonia lasting at least 10 seconds. In addition, theta activity dominates the EEG during the episode, and video recordings document immobility. To distinguish a cataplexy episode from REM sleep after a brief awa...

Prevalence and correlates of insomnia and its impact on quality of life in chinese schizophrenia patients

Conclusion: Insomnia is independently associated with poor QOL. More attention should be paid in clinical practice to the high rate of insomnia in Chinese schizophrenia patients. Keywords: Schizophrenia, insomnia, quality of life, China, Hong Kong (Source: Sleep)

Irregular respiration as a marker of wakefulness during titration of cpap

Conclusions: Despite not detecting all wakefulness, the high positive predictive value suggests that analysis of the respiration signal alone may be a useful indicator of CNS state with potential utility in the control of CPAP in OSAHS. The present study demonstrates the feasibility of automating the detection of IrREG. Keywords: Sleep disordered breathing, artificial neural network, autotitration, arousal and wakefulness, obstructive sleep apnea (Source: Sleep)

Development of nrem sleep instability-continuity (cyclic alternating pattern) in healthy term infants aged 1 to 4 months

Conclusions: With this study, we provide the first data on CAP analysis in infants from 1 to 4 months of life, and we found that there is a transitory period when tracè alternant disappears and CAP events begin to occur. Furthermore, we suggest that the more appropriate time of life when CAP analysis can be first performed is related to the appearance of mature stage 2 NREM with spindles and slow delta waves mixed with theta waves, at approximately 3 months of life. Keywords: Infant, cyclic alternating pattern, arousal, tracè alternant (Source: Sleep)

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Insomnia did not predict incident hypertension in older adults in the cardiovascular health study

Conclusions:Insomnia did not predict hypertension in this older cohort which was free of hypertension at baseline. Difficulty falling asleep was associated with reduced risk of hypertension in non-African American men. Keywords: Aging, sleep complaints, cardiovascular disease, epidemiology, African American (Source: Sleep)

Prediction of obstructive sleep apnea with craniofacial photographic analysis

(Source: Sleep)

Craniofacial phenotyping in obstructive sleep apnea – a novel quantitative photographic approach

Conclusions: Craniofacial phenotypic differences in OSA in Caucasian subjects can be demonstrated using a photographic analysis technique. Keywords: obstructive sleep apnea; craniofacial abnormalities; photogrammetry; phenotype (Source: Sleep)

Effects and side-effects of surgery for snoring and obstructive sleep apnea – a systematic review

Conclusions: Only a small number of randomized controlled trials with a limited number of patients assessing some surgical modalities for snoring or sleep apnea are available. These studies do not provide any evidence of effect from laser-assisted uvulopalatoplasty or radiofrequency ablation on daytime sleepiness, apnea reduction, quality of life or snoring. We call for research of randomized, controlled trials of surgery other than uvulopalatopharyngoplasty and uvulopalatoplasty, as they are related to a high risk of long-term side-effects, especially difficulty swallowing. Keywords: Sleep apnea syndromes, snoring, surgery, adverse effects, meta-analysis (Source: Sleep)

Re-redefining success in airway surgery for obstructive sleep apnea

(Source: Sleep)

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Discovery of the dreaming sleep stage: a recollection

(Source: Sleep)

Heart failure, central sleep apnea, cpap, and arousals: another piece of the puzzle

A commentary on Ruttanaumpawan et al. Effect of Continuous Positive Airway Pressure on Sleep Structure in Heart Failure Patients with Central Sleep Apnea. Sleep 2009;32:91-98. (Source: Sleep)

Craniofacial profile assessment in patients with obstructive sleep apnea

A commentary on Lee et al. Craniofacial Phenotyping in Obstructive Sleep Apnea – A Novel Quantitative Photographic Approach. SLEEP 2008;32:37-45. and Lee et al. Prediction of Obstructive Sleep Apnea with Craniofacial Photographic Analysis. Sleep 2009;32:46-52. (Source: Sleep)

A human model that suggests a role for sleep in the cognitive neuropsychology of ptsd and recovery

(Source: Sleep)

Effect of continuous positive airway pressure on sleep structure in heart failure patients with central sleep apnea

Conclusion: These data suggest that attenuation of CSA by CPAP does not reduce arousal frequency in HF patients. We conclude that arousals were not mainly a consequence of CSA, and may not have been acting as a defense mechanism to terminate apneas in the same way they do in OSA. Keywords:Arousal, sleep structure, central sleep apnea, sleep physiology (Source: Sleep)

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Race and financial strain are independent correlates of sleep in midlife women: the swan sleep study

Conclusions: Independent relationships between race and financial strain with sleep were observed despite statistical adjustment for other factors that might account for these relationships. Results do not suggest that assessed indices of SES moderate the race-sleep relationship, perhaps due to too few women of low SES in the study. Keywords: sleep; power spectral analysis; PSQI; midlife women; menopause; race; SES (Source: Sleep)

The economic burden of insomnia: direct and indirect costs for individuals with insomnia syndrome, insomnia symptoms, and good sleepers

Conclusions: This study suggests that the economic burden of insomnia is very high, with the largest proportion of all expenses (76%) attributable to insomnia-related work absences and reduced productivity. As the economic burden of untreated insomnia is much higher than that of treating insomnia, future clinical trials should evaluate the cost-benefits, cost-utility, and cost-effectiveness of insomnia therapies. Keywords: Insomnia, epidemiology, health economics (Source: Sleep)

Sleep promotes generalization of extinction of conditioned fear

Conclusions: After sleep, extinction memory generalized from an extinguished conditioned stimulus to a similarly conditioned but unextinguished stimulus. Clinically, adequate sleep may promote generalization of extinction memory from specific stimuli treated during exposure therapy to similar stimuli later encountered in vivo. Keywords: Fear conditioning, extinction, generalization, human, emotional memory (Source: Sleep)

Sleep and coronary artery calcification

Several medical bloggers have posted about a recent study in which increased sleep time was associated with a decreased incidence of coronary artery disease (as measured by coronary artery calcification).The problem with these observational studies looking at sleep duration and mortality/morbidity is that they don't distinguish between 1) voluntary sleep deprivation, 2) primary insomnia, and 3) insomnia secondary to medical/sleep disorders.How is a doctor to use the data from this study???I doubt writing a prescription for a sleeping pill would improve someone's coronary artery calcification score. However, advising someone with voluntary sleep deprivation (due to work pressures, etc) to extend their sleep hours might (if they take your advice)- I base this conclusion on prior studies whic...

Insomnia costs billions in lost productivity

Title: Insomnia Costs Billions in Lost ProductivityCategory: Health NewsCreated: 1/2/2009 2:00:00 AMLast Editorial Review: 1/2/2009 (Source: MedicineNet Sleep General)

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Smoking: kick the habit

Title: Smoking: Kick the HabitCategory: Health NewsCreated: 1/2/2009 2:00:00 AMLast Editorial Review: 1/2/2009 (Source: MedicineNet Sleep General)

I resolve ... to sleep better

As the world welcomes 2009 and millions commit themselves to better living, take a moment to learn 10 ways you can improve your sleep tonight ... and your life in... (Source: About Sleep Disorders)

Applications of transcranial magnetic stimulation in sleep medicine.

Authors: Civardi C, Collini A, Monaco F, Cantello R Transcranial magnetic stimulation (TMS) is a new method, developed nearly 20 years ago, that allows the study of cortical excitability. The whole brain undergoes profound changes in sleep. Motor evoked potentials (MEPs) have been used to trace the effects of sleep on cortical excitability and to the corticomotoneuron connections. Although in the past some technical aspects limited the application of TMS in sleep, recently we observed a new explosion of interest in this field. The main body of data was gathered on sleep physiology, but its diseases or syndromes were also studied in detail. Many single and paired pulse-TMS variables were applied. Moreover, TMS variables were investigated as a potential tool for the diagnosis or the diff...

Health tip: prevent headaches during pregnancy

Title: Health Tip: Prevent Headaches During PregnancyCategory: Health NewsCreated: 12/27/2008 2:00:00 AMLast Editorial Review: 12/29/2008 (Source: MedicineNet Sleep General)

Nighttime movements may predict later risk of dementia and parkinson's disease

Individuals who kick or cry out during their sleep may be at increased risk of developing dementia or Parkinson's disease later in life, according to a recent study published in... (Source: About Sleep Disorders)

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Tips to ease an aching back

Title: Tips to Ease an Aching BackCategory: Health NewsCreated: 12/26/2008 2:00:00 AMLast Editorial Review: 12/26/2008 (Source: MedicineNet Sleep General)

Using a social justice approach to prevent the mental health consequences of heterosexism

This article describes Albee’s framework in the context of minority stress theory as it applies to LGB people and suggests activities mental health professionals can engage in to help prevent the psychological consequences of heterosexism. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10935-008-0166-4Authors Connie R. Matthews, Slippery Rock University Slippery Rock PA USAEve M. Adams, New Mexico State University Las Cruces NM USA Journal The Journal of Primary PreventionOnline ISSN 1573-6547Print ISSN 0278-095X (Source: The Journal of Primary Prevention)

American academy of dental sleep medicine continuing education offerings.

Authors: PMID: 19104884 [PubMed - in process] (Source: Sleep and Breathing)

Report on the 3rd international symposium on dental sleep medicine of the european academy of dental sleep medicine (eadsm), berlin, 3-4 october 2008.

Report on the 3rd International Symposium on Dental Sleep Medicine of the European Academy of Dental Sleep Medicine (EADSM), Berlin, 3-4 October 2008. Sleep Breath. 2009 Mar;13(1):115-6 Authors: PMID: 19104885 [PubMed - in process] (Source: Sleep and Breathing)

Langzeit-compliance der cpap-therapie bei obstruktivem schlafapnoe-syndrom

Summary CPAP (continuous positive airway pressure) is the therapy of choice for obstructive sleep apnea syndrome (OSAS). About 70 % of patients on CPAP use their device for at least 70 % of nights with an application time of at least 4 hours per night. Compared to subjective CPAP-application time, pressure monitors show that patients tend to overestimate their CPAP compliance by about one hour; nevertheless pressure monitoring has shown that more than 70 % of patients use their CPAP device for at least 4 hours per night. Even in the long-term application of CPAP it has been shown that approximately 60 % of patients use their CPAP device for more that 5 hours per night. Severity of breathing disorder and disturbance of sleep architecture, degree of daytime sleepiness and ...

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Effekt von kontrolluntersuchungen bei patienten mit obstruktivem schlafapnoe-syndrom: stellenwert der bilevel- und automatischen cpap-therapie

Summary Introduction Automatic positive airway pressure (APAP) and bilevel devices are used as alternatives to continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea syndrome (OSAS). However, the question still remains what the advantages of these options are or if there are special indications in patients with difficult to treat OSAS. Methods A Medline search was performed using the key words “bilevel OR bipap AND sleep apnea” and “APAP OR automatic CPAP AND sleep apnea”. For bilevel and APAP 14 studies for each were included in the further evaluation. Results and conclusions Both bilevel and APAP have proved to be equally effective as compared to CPAP. Therefore, CPAP still represents th...

Schulung bei patienten mit obstruktivem schlafapnoe-syndrom im rahmen von nachsorgekonzepten

Summary Introduction The compliance and adherence with continuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnea syndrome (OSAS) remain suboptimal. Education strategies in OSAS patients may increase the nightly use of CPAP therapy. In this article the evidence-based data of different education strategies in OSAS patients are reviewed. Methods MEDLINE research; items sleep apnea AND education. Limits: Clinical trial; humans. Results Many studies have been published indicating that education may improve treatment compliance in patients with obstructive sleep apnea (evidence grade 1b and 2b). Education strategies include written information, single or group education sessions and telephone call...

Evidenzbestimmung zu kontrolluntersuchungen bei positiver druckbeatmung von patienten mit schlafbezogenen atmungsstörungen (ekopas)

Evidenzbestimmung zu Kontrolluntersuchungen bei positiver Druckbeatmung von Patienten mit schlafbezogenen Atmungsstörungen (EKOPAS) Content Type Journal ArticleCategory EDITORIALDOI 10.1007/s11818-008-0369-1Authors K.-H. Rühle, Universität Witten-Herdecke Klinik für Pneumologie, Klinik Ambrock Ambrocker Weg 60 58091 Hagen Germany Journal Somnologie - Schlafforschung und SchlafmedizinOnline ISSN 1439-054XPrint ISSN 1432-9123 Journal Volume Volume 12 Journal Issue Volume 12, Number 4 / December, 2008 (Source: Somnologie - Schlafforschung und Schlafmedizin)

Mund und maskenleckage bei kontrolluntersuchungen

This study is suggestive of the negative effect of mouth breathing on the compliance of CPAP. Therefore, when insufficient compliance is uncovered, check-ups should quantify the mucosa side effects and the leakage data from the CPAP machine. Content Type Journal ArticleCategory ORIGINALARBEITDOI 10.1007/s11818-008-0368-2Authors Georg Nilius, Universität Witten-Herdecke Klinik für Pneumologie, Klinik Ambrock Ambrocker Weg 60 58091 Hagen Germany Journal Somnologie - Schlafforschung und SchlafmedizinOnline ISSN 1439-054XPrint ISSN 1432-9123 Journal Volume Volume 12 Journal Issue Volume 12, Number 4 / December, 2008 (Source: Somnologie - Schlafforschung und Schlafmedizin)

Maskenoptimierung im rahmen von kontrolluntersuchungen

Summary The acceptance of positive airway pressure therapy depends on the adequate selection of the pressure and good adaptation of an appropriate mask. Most often a nasal mask is preferred. Oronasal and oral masks as well as nasal pillows represent good alternatives to nasal masks. The presented studies which partly examine a change from one mask type to another show in only one study an evidence level of 1b. The other protocols often concern case control studies. If during check-ups a poor acceptance of the mask is realized, an individual selection and accommodation will become necessary. Long-term follow-up, application of questionnaires concerning long-term acceptance, and standards for prognostic criteria are lacking so far. Content Type Journal ArticleCategory ...

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Deutsche gesellschaft für schlafforschung und schlafmedizin

Deutsche Gesellschaft für Schlafforschung und Schlafmedizin Content Type Journal ArticleCategory MITTEILUNGSBLATTDOI 10.1007/s11818-008-0366-4 Journal Somnologie - Schlafforschung und SchlafmedizinOnline ISSN 1439-054XPrint ISSN 1432-9123 Journal Volume Volume 12 Journal Issue Volume 12, Number 4 / December, 2008 (Source: Somnologie - Schlafforschung und Schlafmedizin)

Nachsorge und begleitmedikation bei osas: therapie der kardiovaskulären komplikationen und persistierender schläfrigkeit

Summary More than a half of OSAS patients are additionally treated with a medication, mostly due to cardiovascular comorbidity or a metabolic syndrome. A follow-up to control CPAP therapy and to make an adjustment of the medication, for instance with antihypertensives, is reasonable. The grade of evidence for this conclusion is low (EG 3), but it is known, that compliance is dependent on a close follow- up, especially in the first weeks. There are promising new medical therapies to treat symptoms of OSAS, especially to treat persistent or new developed excessive daytime sleepiness (EG 1b–2b). Content Type Journal ArticleCategory ORIGINALARBEITDOI 10.1007/s11818-008-0367-3Authors Alexander Blau, Charité – Universitätsmedizin Berlin Interdisziplinäres Sc...

Sleep longer, help your heart

Title: Sleep Longer, Help Your HeartCategory: Health NewsCreated: 12/24/2008Last Editorial Review: 12/24/2008 (Source: MedicineNet Sleep General)

Oral spray sleep drug zolpimist approved

Title: Oral Spray Sleep Drug Zolpimist ApprovedCategory: Health NewsCreated: 12/23/2008Last Editorial Review: 12/23/2008 (Source: MedicineNet Sleep General)

Predictors of restless legs syndrome in pregnancy: a hospital based cross sectional survey from pakistan.

The objective of our study was to determine frequency of RLS in pregnant women and predictors of RLS in pregnancy in Pakistan. All pregnant women admitted at The Aga Khan University Hospital for delivery from June to July 2005 were enrolled. Eighty-one of 271 (30%) interviewed women fulfilled the diagnostic criteria of RLS. One hundred seventeen (43%) of the subjects dropped their haemoglobin during the pregnancy. No significant difference in haemoglobin drop was noted between the RLS group and healthy group. On multivariate analysis family history of RLS (OR: 8.43, CI: 2.32-30.57, p value<0.001), history of RLS in prior pregnancy (OR: 53.74, CI: 6.72-429.8, p value<0. 001), history of RLS in past even when non-pregnant (OR: 12.91, CI: 3.34-49.87, p value<0.001) and haemoglobin of...

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Response from the authors.

Authors: Poceta JS, Kripke D PMID: 19109062 [PubMed - as supplied by publisher] (Source: Sleep Medicine)

Rem sleep behaviour disorder (rbd) and its associations in young patients.

CONCLUSIONS: In a population of patients with RBD presenting to a regional sleep laboratory, more than one-third of patients were <50 y at time of diagnosis. The commonest associated disorder was narcolepsy in patients <50 y, and synucleinopathy in those 50 y. The coexistence of RBD with a NREM parasomnia was not uncommon in cases of idiopathic RBD affecting patients <50 y. PMID: 19109063 [PubMed - as supplied by publisher] (Source: Sleep Medicine)

Welcome to the club: substantial sleep dysfunction also in progressive supranuclear palsy.

Welcome to the club: Substantial sleep dysfunction also in Progressive Supranuclear Palsy. Sleep Med. 2008 Dec 22; Authors: Diederich NJ PMID: 19109064 [PubMed - as supplied by publisher] (Source: Sleep Medicine)

Teasing apart drug treatments and individual symptoms in narcolepsy.

Authors: Lee YJ, Shapiro CM PMID: 19109065 [PubMed - as supplied by publisher] (Source: Sleep Medicine)

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